Measuring Fitness of Kenyan Children with Polyparasitic Infections Using the 20-Meter Shuttle Run Test as a Morbidity Metric

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Show simple item record Bustinduy, Amaya L Thomas, Charles L Fiutem, Justin J Parraga, Isabel M Mungai, Peter L MUCHIRI, ERIC M Mutuku, Francis M KITRON, URIEL King, Charles H. 2017-10-16T09:16:56Z 2017-10-16T09:16:56Z 2011-07-05
dc.identifier.citation B u s t i n d u y A L , T h o m a s C L , F i u t e m J J , P a r r a g a I , M u n g a i P L , e t a l . ( 2 0 1 1 ) M e a s u r i n g F i t n e s s o f K e n y a n C h i l d r e n w i t h P o l y p a r a s i t i c I n f e c t i o n s U s i n g t h e 20-Meter Shuttle Run Test As a Morbidity Metric. PLoS Negl Trop Dis 5(7): e1213. doi:10.1371/journal.pntd.0001213 en_US
dc.description.abstract Background: To date, there has been no standardized approach to the assessment of aerobic fitness among children who harbor parasites. In quantifying the disability associated with individual or multiple chronic infections, accurate measures of physical fitness are important metrics. This is because exercise intolerance, as seen with anemia and many other chronic disorders, reflects the body’s inability to maintain adequate oxygen supply ( VO 2 max) to the motor tissues, which is frequently linked to reduced quality-of-life in terms of physical and job performance. The objective of our study was to examine the associations between polyparasitism, anemia, and reduced fitness in a high risk Kenyan population using novel implementation of the 20-meter shuttle run test (20mSRT), a well-standardized, low-technology physical fitness test. Methodology/Principal Findings: Four villages in coastal Kenya were surveyed during 2009–2010. Children 5–18 years were tested for infection with Schistosoma haematobium (Sh), malaria, filaria, and geohelminth infections by standard methods. After anthropometric and hemoglobin testing, fitness was assessed with the 20 mSRT. The 20 mSRT proved easy to perform, requiring only minimal staff training. Parasitology revealed high prevalence of single and multiple parasitic infections in all villages, with Sh being the most common (25–62%). Anemia prevalence was 45–58%. Using multiply- adjusted linear modeling that accounted for household clustering, decreased aerobic capacity was significantly associated with anemia, stunting, and wasting, with some gender differences. Conclusions/Significance: The 20 mSRT, which has excellent correlation with VO 2, is a highly feasible fitness test for low- resource settings. Our results indicate impaired fitness is common in areas endemic for parasites, where, at least in part, low fitness scores are likely to result from anemia and stunting associated with chronic infection. The 20 mSRT should be used as a common metric to quantify physical fitness and compare sub-clinical disability across many different disorders and community settings. en_US
dc.description.sponsorship TECHNICAL UNIVERSITY OF MOMBASA en_US
dc.language.iso en en_US
dc.publisher PLOS Neglected Tropical Disease en_US
dc.subject aerobic fitnes,multiple chronic infections, children, malaria, filaria, geohelminth, en_US
dc.title Measuring Fitness of Kenyan Children with Polyparasitic Infections Using the 20-Meter Shuttle Run Test as a Morbidity Metric en_US
dc.type Article en_US

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