• Login
    View Item 
    •   Repository Home
    • Journal Articles
    • Department of Environment and Health Sciences
    • View Item
    •   Repository Home
    • Journal Articles
    • Department of Environment and Health Sciences
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Anemia Burden, Types and Associated Risk Factors among Kenyan Human Immunodeficiency Virus-1 and Mycobacterium Tuberculosis Co-infected Injection Substance Users

    Thumbnail
    View/Open
    Budambula Valentine.pdf (413.1Kb)
    Date
    2020-09-01
    Author
    Abonyo Collins
    Shaviya Nathan
    Budambula Valentine
    Were Tom
    Metadata
    Show full item record
    Abstract
    BACKGROUND፡ Although injection substance users and individuals co-infected with Human Immunodeficiency Virus-1 and Mycobacterium tuberculosis suffer marked hematologic derangements, the rates, levels, morphologic types and associated risk factors of anemia among Human immunodeficiency virus and Mycobacterium tuberculosis co infected injection substance users has not been reported in Kenya. METHODS: This cross-sectional study determined anemia rates, levels and morphologic types. Anemia was associated with clinical markers of disease- underweight, immunosuppression and viral load. Complete blood count, CD4 T-cell enumeration and viral load were determined via standard laboratory methods. RESULTS: All injection substance users had higher rates of anaemia (HIV+TB+ ISUs, 79.3%; HIV-TB+ISUs, 70.0%; HIV+TB- ISUs, 56.6% and HIV-TB- ISUs, 56.2%) relative to non-ISUs (16.6%; P<0.05). A significant proportion of HIV+TB+ISUs (47.8%) developed severe anemia than other clinical groups. The commonest morphologic type of anemia in HIV+TB+ISUs was microcytic hypochromic (43.5%) followed by normocytic hypochromic (17.4%) relative to the other clinical groups. HIV+TB+ ISUs with CD4 T-cells <200/uL (OR: 2.94, 95% CI: 1.41-6.13, P=0.004) and CD4 T cells of 200-349/uL (OR: 3.24, 95% CI: 1.66-6.31, P=0.001) associated with higher odds of developing anemia.
    URI
    https://ir.tum.ac.ke/handle/123456789/17445
    Collections
    • Department of Environment and Health Sciences [70]

    Technical University of Mombasa copyright © 2020  University Library
    Contact Us | Send Feedback
    Supported by KUBUNI
     

     

    Browse

    All of RepositoryCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

    My Account

    LoginRegister

    Statistics

    View Usage Statistics

    Technical University of Mombasa copyright © 2020  University Library
    Contact Us | Send Feedback
    Supported by KUBUNI