Department of Pure and Applied Sciences
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Recent Submissions
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Antimalarial Activity of Nigella sativa L. Seed Extracts and Selection of Resistance in Plasmodium berghei ANKA in a Mouse Model
(Hindawi - Journal of Pathogens, 2021-02-03)Background. Chemotherapy plays a crucial role in malaria control. However, the main obstacle to treatment has been the rise of parasite resistance to most antimalarial drugs. Artemisinin-based combination therapies (ACTs) ... -
Parasitic Infections in Pregnancy Decrease Placental Transfer of Antipneumococcus Antibodies
(AMERICAN SOCIETY FOR MICROBIOLOGY, 2017)Many factors can influence maternal placental antibody transfer to the fetus, which confers important immune protection to the newborn infant. However, little is known about the effect of maternal parasitic infection on ... -
ELASTIC FIBRE SYSTEM IN THE SHAFT OF ADULT HUMAN PENIS
(Anatomy Journal of Africa, 2015)Elastic fibres play a central role in functioning of the penis. Detailed animal studies have quantified elastic and collagen fibre content in rat and rabbit penis. Though rabbit model is similar to human penis, it is ... -
CONTROVERSY ABOUT EMBRYOGENESIS AND ORGANISATION OF HUMAN FEMALE URETHRA: A REVIEW
(East African Medical, 2014)Objective: To assess current knowledge on development and associated structures. Data sources: Current scientific publications in the pubmed data base on the development of human female urethra were reviewed. The ... -
CONTROVERSY ABOUT EMBRYOGENESIS AND ORGANISATION OF HUMAN FEMALE URETHRA: A REVIEW
(East African Medical, 2014)Objective: To assess current knowledge on development and associated structures. Data sources: Current scientific publications in the pubmed data base on the development of human female urethra were reviewed. The ... -
CD4 T-LYMPHOCYTE SUBSETS IN WOMEN WITH INVASIVE CERVICAL CANCER IN KENYA
(East African Medical, 2013)Objective: Invasive cervical cancer (ICC) and HIV are common in sub-Sahara Africa. Both ICC and HIV are immunosuppressive, and are associated with decreased CD4 and CD8 profiles. In a group of women with ICC starting ... -
Heavy metal and associated antibiotic resistance of fecal coliforms, fecal streptococci and pathogens isolated from wastewaters of abattoirs in Nairobi, Kenya
(Kenyatta University, 2013)Objective: The pollution of the environment with toxic heavy metals is increasing globally with industrial progress. Microorganisms can be good bio-accumulators of particulate and soluble forms of heavy metals and ... -
Anopheles gambiae: historical population decline associated with regional distribution of insecticide-treated bed nets in western Nyanza Province, Kenya
(Bayoh et al. Malaria Journal, 2010)Background: High coverage of insecticide-treated bed nets in Asembo and low coverage in Seme, two adjacent communities in western Nyanza Province, Kenya; followed by expanded coverage of bed nets in Seme, as the Kenya ... -
Modulation of Cognition: The Role of Gnidia glauca on Spatial Learning and Memory Retention in High-Fat Diet-Induced Obese Rats
(Hindawi Neural Plasticity, 2019-09)Chronic exposures to high-fat diets are linked to neuropathological changes that culminate in obesity-related cognitive dysfunction and brain alteration. Learning, memory performance, and executive function are the main ... -
Anti-obesity effects of dichloromethane leaf extract of Gnidia glauca in high fat diet-induced obese rats
(Elsevier, 2019-10)Obesity is a chronic metabolic disorder characterized by increased adipose tissue mass due to positive energy balance. Prescription of anti-obesity drugs can be useful adjuncts to diet and exercise for obese patients who ... -
In Vitro Antioxidant Properties of Dichloromethanolic Leaf Extract of Gnidia glauca (Fresen) as a Promising Antiobesity Drug
(Sage, 2019-09)The acquisition of ethnobotanical information from traditional practitioners remains an empirical aspect of understanding the ethnopharmacology research. However, integration of information on chemical composition of plant ... -
Antipyretic potential of dichloromethane leaf extract of Eucalyptus globulus (Labill) and Senna didymobotrya (Fresenius) in rats models
(2019-11)Fever is managed using synthetic drugs such as aspirin, paracetamol among others. Synthetic drugs are associated with many side effects. Herbal medicines form alternative therapy since they possess fewer side effects and ... -
Effects of DCM Leaf Extract of Gnidia glauca (Fresen) on Locomotor Activity, Anxiety, and Exploration-Like Behaviors in High-Fat Diet-Induced Obese Rats
(Hindawi Behavioural Neurology, 2019-12)Obesity is the main component of metabolic syndromes involving distinct etiologies that target different underlying behavioral and physiological functions within the brain structures and neuronal circuits. An alteration ... -
Diversity of fungi in sediments and water sampled from the hot springs of Lake Magadi and Little Magadi in Kenya
(African Journal of Microbiology Research, 2016-03-14)Lake Magadi and Little Magadi are saline, alkaline lakes lying in the southern part of Kenyan Rift Valley. Their solutes are supplied by a series of alkaline hot springs with temperatures as high as 86°C. Previous ... -
Determination of Cyanogenic Compounds Content in Transgenic Acyanogenic Kenyan Cassava (Manihot esculenta Crantz) Genotypes: Linking Molecular Analysis to Biochemical Analysis
(Analytical & Bioanalytical Techniques, 2015-09-23)Being the fourth most important crop in the developing countries surpassed only by maize, rice and sugarcane as a source of calories, cassava (Manihot esculenta Crantz) is doubtlessly a famine reserve crop due to its drought ... -
Impact of Marine Woodborers Dicyathifer mannii, Sphaeroma terebrans and Cirolana sp. on the Mangroves of the Kenyan Coast
(International Journal of Ecology and Environmental Sciences, 2015)Three species of woodborers from marine mangrove plants at Mida Creek, Tudor Creek and Gazi Bay along the Kenyan coast are identified. The relationship between the borers and the host mangrove plants (Avicennia, Sonneratia, ... -
Barriers to Full Immunization Coverage of Under Five Years Children in Benadir Region, Somalia
(ResearcgGate, 2016-09)Immunization is an important public health intervention aimed at reducing child mortality and morbidity in line with the fourth goal of the Millennium Development Goals. It is an important means for controlling six ... -
Homeobox Is Pivotal for OsWUS Controlling Tiller Development and Female Fertility in Rice
(G3: Genes, Genomes, Genetics, 2016-05-17)OsWUS has recently been shown to be a transcription factor gene critical for tiller development and fertility in rice. The OsWUS protein consists of three conserved structural domains, but their biological functions are ... -
454 Pyrosequencing-based assessment of bacterial diversity and community structure in termite guts, mounds and surrounding soils
(SpringerOpen, 2015)Termites constitute part of diverse and economically important termite fauna in Africa, but information on gut microbiota and their associated soil microbiome is still inadequate. In this study, we assessed and compared ... -
ULTRASTRUCTURAL MICROMORPHOLOGY OF BULBINE ABYSSINICA A. RICH. GROWING IN THE EASTERN CAPE PROVINCE, SOUTH AFRICA
(University of Fort Hare, 2015)The genus Bulbine (Asphodelaceae) comprises about 40 species in South Africa. Bulbine abyssinica is a succulent member of the genus that occurs from the Eastern Cape, through Swaziland, Lesotho, ...