Department of Pure and Applied Sciences
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Recent Submissions
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Phytochemical analysis and safety evaluation of ethanol roots extract of Erythrina sacleuxii hua in Wistar albino rats
(Journal of Medicinal Plants Research, 2022-04)Erythrina sacleuxii, one of five Erythrina species found in Kenya, is a stiffly multi-branched deciduous tree reported to have antiplasmodial, antifungal, anti-bacterial and anti-cancer activities. This study aimed at ... -
Malaria Transmission After Artemether-Lumefantrine and Dihydroartemisinin-Piperaquine: A Randomized Trial
(y Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com., 2013-03-06)Artemisinin-based combination therapy (ACT) reduces the potential for malaria transmission, compared with non-ACTs. It is unclear whether this effect differs between ACTs. -
Antimalarial Activity of Nigella sativa L. Seed Extracts and Selection of Resistance in Plasmodium berghei ANKA in a Mouse Model
(Hindawi Journal of Pathogens, 2021-02-03)Chemotherapy plays a crucial role in malaria control. However, the main obstacle to treatment has been the rise of parasite resistance to most antimalarial drugs. Artemisinin-based combination therapies (ACTs) remain the ... -
Streptococcus pneumoniae serotype epidemiology among PCV-10 vaccinated and unvaccinated children at Gertrude’s Children’s Hospital, Nairobi County: a cross-sectional study
(Faculty of 1000 Ltd, 2018)Background: Serotype replacement and emergence of multidrug resistant S. pneumoniae has exacerbated the need for continuous regional serotype surveillance especially in the developing world. We investigated S. ... -
Seroprevalence of foot-and-mouth disease virus in cattle herds raised in Maasai Mara ecosystem in Kenya
(Elsevier, 2020)A cross-sectional study was carried out to determine foot-and-mouth disease (FMD) seroprevalence and identify risk factors of exposure among cattle herds raised in three zones with different types of land use and progressively ... -
MOLECULAR TECHNIQUE UTILISING SPUTUM FOR DETECTING WUCHERERIA BANCROFTI INFECTIONS IN MALINDI, KENYA
(2008)Background: Lymphatic filariasis is a tropical parasitic disease which has been identified for elimination by 2020 through mass drugs administration. There is a major problem in its diagnosis and sensitive surveillance ... -
Differential Induction of Proteins in Anopheles gambiae sensu stricto (Diptera: Cullicidae) Larvae in Response to Heavy Metal Selection
(Cambridge University Press, 2006)Investigations were conducted to establish the magnitude and pattern of differential expression of proteins due to generational selection of third instar An. gambiae s.s. larvae by cadmium, copper and lead heavy metals, ... -
Biosafety education relevant to genetically engineered crops for academic and non-academic stakeholders in East Africa
(Pontificia Universidad Católica de Valparaíso, 2009)Financial support: The work included in this publication was sponsored by the United States Agency for International Development through the Program for Biosafety Systems implemented by the International Food Policy ... -
Properties of a blood-meal-induced midgut lectin from the tsetse fly Glossina morsitans
(Springer-Verlag, 1995)The properties of a blood-meal-induced lectin (agglutinin) from the midgut of Glossina morsitans capable of agglutinating Trypanosoma brucei were studied in vitro. The midgut homogenate from flies that had been fed twice ... -
Pathogenic Escherichia coli and food handlers in luxury hotels in Nairobi, Kenya
(Elsevier, 2009)Background: The epidemiology and virulence properties of pathogenic Escherichia coli among food handlers in tourist destination hotels in Kenya are largely uncharacterized. Method: This cross-sectional study among ... -
Zoonotic pathogen seroprevalence in cattle in a wildlife–livestock interface, Kenya
(Springer US, 2019)A cross-sectional study was conducted to determine the seroprevalence of Brucella spp. and Leptospira spp. and risk factors of exposure in cattle in three zones with varying land use types and wildlife– livestock ... -
CHARACTERIZATION OF ALGAE OIL (OILGAE) AND ITS POTENTIAL AS BIOFUEL IN KENYA
(Journal of Applied Phytotechnology in Environmental Sanitation, 2012)A survey of microalgae biodiversity in three Kenyan Rift valley lakes identified high oil yielding species abundantly distributed naturally. The species were cultured in BBM and BG-11 media to obtain pure clones and ... -
Expression of metallothionein and α-tubulin in heavy metaltolerant Anopheles gambiae sensu stricto (Diptera: Culicidae)
(Academic Press, 2010)Anopheles mosquitoes have been shown to adapt to heavy metals in their natural habitats. In this study we explored the possibility of using Anopheles gambiae sensu stricto as bio-reporters for environmental heavy metal ... -
Analysis of genetic diversity in Eucalyptus grandis (Hill ex Maiden) seed sources using inter simple sequence repeats (ISSR) molecular markers
(2008)Eucalyptus grandis is an economically important tree species that is native to the Australian continent and its northern neighbours, where it is grown primarily for its hard wood timber and pulp for paper industries. It ... -
Distribution of indigenous strains of atoxigenic and toxigenic Aspergillus flavus and Aspergillus parasiticus in maize and peanuts agro-ecological zones of Kenya
(BioMed Central, 2015)Background Grains of important food and export crops in Africa are susceptible to contamination by toxin-producing moulds. Aflatoxins are mycotoxins associated with liver damage and cancer in humans and animals. These ... -
A participatory epidemiological study of major cattle diseases amongst Maasai pastoralists living in wildlife-livestock interfaces in Maasai Mara, Kenya
(Springer Netherlands, 2019)Livestock-wildlife interactions promote the transmission of a wide range of infectious diseases that constraint livestock production. We used a participatory appraisal approach to find out and rank infectious diseases of ... -
Uncovering the tracks of a recent and rapid invasion
(Blackwell Publishing Ltd, 2009)Phytophagous insects of the genus Bactrocera are among the most economically important invasive fruit fly pests. In 2003, an unknown Bactrocera species was found in Kenya. First identified as an ‘aberrant form’ of the ... -
Detection of trypanosomes in small ruminants and pigs in western Kenya: important reservoirs in the epidemiology of sleeping sickness?
(BioMed Central, 2005)Background: Trypanosomosis is a major impediment to livestock farming in sub-Saharan Africa and limits the full potential of agricultural development in the 36 countries where it is endemic. In man, sleeping sickness is ... -
Dual African Origins of Global Aedes aegypti s.l. Populations Revealed by Mitochondrial DNA
(Public Library of Science, 2013)Background: Aedes aegypti is the primary global vector to humans of yellow fever and dengue flaviviruses. Over the past 50 years, many population genetic studies have documented large genetic differences among global ... -
Prevalence of metabolic syndrome among an urban population in Kenya
(American Diabetes Association, 2012)OBJECTIVE Developing countries are undergoing an epidemiologic transition accompanied by increasing burden of cardiovascular disease (CVD) linked to urbanization and lifestyle modifications. Metabolic syndrome is a cluster ...