Browsing Department of Medical Sciences by Title
Now showing items 4-10 of 10
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Lack of Fetuin-A ( 2-HS-Glycoprotein) Reduces Mammary Tumor Incidence and Prolongs Tumor Latency via the Transforming Growth Factor-Signaling Pathway in a Mouse Model of Breast Cancer
(2015-10-21)The present analyses were done to define the role of fetuin-A (Fet) in mammary tumorigenesis using the polyoma middle T antigen (PyMT) transgenic mouse model. We crossed Fet-null mice in the C57BL/6 background with ... -
MHC-Ig Dimers: The next Frontier in Transplantation Immunology
(International Journal of Biomedical Research, 2015-09)Organ transplantation offers hope to a variety of patients with terminal functioning organs and tissues. This is currently made possible by administration of general immunosuppressive drugs. To date, inducing tolerance to ... -
The Occurrence of Glucose 6 Phosphate Dehydrogenase Deficiency amongst Blood Donors at the Regional Blood Transfusion Centre-Mombasa, Kenya
(Pharmaceutical Society of Kenya, 2018-09)Glucose-6-phosphate dehydrogenase deficiency (G6PDd) is an X-linked hereditary genetic defect that is estimated to affect 400 million people worldwide. This deficiency is associated with hemolytic disorders that may manifest ... -
Occurrence of red blood cell abnormalities in donor blood donated at the regional blood transfusion centre, Mombasa, Kenya
(2023-01)During transfusion, components of blood including red blood cells, platelets and plasma are directly administered into the recipient to treat conditions such as anaemia and haemostatic deficiencies. In most cases, effective ... -
Prevalence of Metabolic Syndrome Among an Urban Population in Kenya
(American Diabetes Association, 2012-01)Developing countries are undergoing an epidemiologic transition accompanied by increasing burden of cardiovascular disease (CVD) linked to urbanization and lifestyle modifications. Metabolic syndrome is a cluster of CVD ... -
Purification and characterization of a midgut lectin-trypsin complex from the tsetse fly Glossina Iongipennis
(Springer-Link, 1995-04)A blood-meal-induced lectin (agglutinin) with proteolytic activity was isolated from midgut extracts ofGlossina longipennis by a two-step procedure involving anion-exchange chromatography. It is a glycoprotein [native ... -
Spatial Temporal Modelling of Tuberculosis in Kenya Using Small Area Estimation
(International Journal of Science and Research (IJSR), 2015)Tuberculosis (TB) is a disease which continues to be of public health importance, and is characterized with varying distribution across regions depending on socio-economic status, HIV burden and efficiency of the health ...