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dc.contributor.authorTemmerman, M
dc.contributor.authorGichangi, P
dc.contributor.authorFonck, K
dc.contributor.authorApers, L
dc.contributor.authorClaeys, P
dc.contributor.authorRenterghem, L Van
dc.contributor.authorKiragu, D
dc.contributor.authorKaranja, G
dc.contributor.authorAchola, J Ndinya
dc.contributor.authorBwayo, J
dc.date.accessioned2024-02-16T10:43:00Z
dc.date.available2024-02-16T10:43:00Z
dc.date.issued2000
dc.identifier.citationTemmerman, M., Gichangi, P., Fonck, K., Apers, L., Claeys, P., Van Renterghem, L., ... & Bwayo, J. (2000). Effect of a syphilis control programme on pregnancy outcome in Nairobi, Kenya. Sexually Transmitted Infections, 76(2), 117.en_US
dc.identifier.other10.1136/sti.76.2.117
dc.identifier.urihttp://ir.tum.ac.ke/handle/123456789/17394
dc.description10.1136/sti.76.2.117en_US
dc.description.abstractObjectives: To assess the impact of a syphilis control programme of pregnant women on preg nancy outcome in Kenya. Method: Women who came to deliver to Pumwani Maternity Hospital (PMH) between April 1997 and March 1998 were tested for syphilis. Reactive rapid plasma reagin (RPR) tests were titrated and confirmed with treponema haemagglutination test (TPHA). Equal numbers of RPR and TPHA negative women were enrolled. Antenatal syphilis screening and treatment history were examined from the antenatal cards. Results: Of 22 466 women giving birth, 12 414 (55%) were tested for syphilis. Out of these, 377 (3%) were RPR reactive of whom 296 were confirmed by TPHA. Syphilis seroreactive women had a more risky sexual behaviour and coexistent HIV antibody positivity; 26% were HIV sero positive compared with 11% among syphilis negative mothers. The incidence of adverse obstet ric outcome defined as low birth weight and stillbirth, was 9.5%. Syphilis seropositive women had a higher risk for adverse obstetric outcome (OR 4.1, 95% CI 2.4–7.2). Antenatal treatment of RPR reactive women significantly improved pregnancy outcome but the risk of adverse outcome remained 2.5-fold higher than the risk observed in uninfected mothers. Conclusions: These data confirm the adverse eVect of syphilis on pregnancy outcome. This study also shows the eYcacy of antenatal testing and prompt treatment of RPR reactive mothers on pregnancy outcome.en_US
dc.description.sponsorshipTECHNICAL UNIVERSITY OF MOMBASAen_US
dc.language.isoenen_US
dc.publisherBMJ Publishing Groupen_US
dc.subjectsyphilis testingen_US
dc.subjectpregnancy outcomeen_US
dc.subjectKenyaen_US
dc.titleEffect of a syphilis control programme on pregnancy outcome in Nairobi, Kenyaen_US
dc.typeArticleen_US


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