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dc.contributor.authorVu, David M
dc.contributor.authorBanda, Tamara
dc.contributor.authorTeng, Crystal Y
dc.contributor.authorHeimbaugh, Chelsea
dc.contributor.authorMuchiri, Eric M
dc.contributor.authorMungai, Peter L
dc.contributor.authorMutuku, Francis M.
dc.contributor.authorBrichard, Julie
dc.contributor.authorGildengorin, Ginny
dc.contributor.authorBorland, Erin M
dc.contributor.authorPowers, Ann M
dc.contributor.authorKitron, Uriel
dc.contributor.authorKing, Charles H
dc.contributor.authorLaBeaud, A. Desiree
dc.date.accessioned2021-06-04T09:15:52Z
dc.date.available2021-06-04T09:15:52Z
dc.date.issued2016-09
dc.identifier.urihttps://ir.tum.ac.ke/handle/123456789/17400
dc.description.abstractDengue virus (DENV) and West Nile virus (WNV) are important reemerging arboviruses that are underrecognized in many parts of Africa due to lack of surveillance. As a part of a study on flavivirus, alphavirus, and parasite exposure in coastal Kenya, we measured neutralizing antibody against DENV and, to evaluate assay specificity, WNV in serum samples that tested positive for serum anti-DENV IgG by enzyme-linked immunosorbent assay. Of 830 anti-DENV IgG-positive samples that were tested for neutralizing activity, 488 (58.8%) neutralized DENV and 94 (11.3%) neutralized WNV. Of children ≤ 10 years of age, 23% and 17% had serum neutralizing antibody to DENV and WNV, respectively, indicating that DENV and WNV transmission has occurred in this region within the past decade. The results suggest that ongoing DENV and WNV transmission continues on the coast of Kenya and supports a need for routine arboviral surveillance in the area to detect and respond to future outbreaks.en_US
dc.language.isoenen_US
dc.publisherThe American Society of Tropical Medicine and Hygieneen_US
dc.subjectDengueen_US
dc.subjectWest Nile Virusen_US
dc.subjectCoastal Kenyaen_US
dc.titleDengue and West Nile Virus Transmission in Children and Adults in Coastal Kenyaen_US
dc.typeArticleen_US


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