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dc.contributor.authorHeath, Claire J
dc.contributor.authorGrossi-Soyster, Elysse N
dc.contributor.authorNdenga, Bryson A
dc.contributor.authorMutuku, Francis M
dc.contributor.authorSahoo, Malaya K
dc.contributor.authorNgugi, Harun N
dc.contributor.authorNbakaya, Joel O
dc.contributor.authorSiema, Peter
dc.contributor.authorKitron, Uriel
dc.contributor.authorZahiri, Nayer
dc.contributor.authorHortion, Jimmy
dc.contributor.authorWaggoner, Jesse J
dc.contributor.authorKing, Charles H
dc.contributor.authorPinsky, Benjamin A
dc.contributor.authorLaBeaud, A. Desiree
dc.date.accessioned2021-06-08T12:54:27Z
dc.date.available2021-06-08T12:54:27Z
dc.date.issued2020-06-19
dc.identifier.urihttps://ir.tum.ac.ke/handle/123456789/17422
dc.description.abstractArboviruses are among the most important emerging pathogens due to their increasing pub lic health impact. In Kenya, continued population growth and associated urbanization are conducive to vector spread in both urban and rural environments, yet mechanisms of viral amplification in vector populations is often overlooked when assessing risks for outbreaks. Thus, the characterization of local arbovirus circulation in mosquito populations is impera tive to better inform risk assessments and vector control practices. Aedes species mosqui toes were captured at varying stages of their life cycle during different seasons between January 2014 and May 2016 at four distinct sites in Kenya, and tested for chikungunya (CHIKV), dengue (DENV) and Zika (ZIKV) viruses by RT-PCR. CHIKV was detected in 45 (5.9%) and DENV in 3 (0.4%) mosquito pools. No ZIKV was detected. Significant regional variation in prevalence was observed, with greater frequency of CHIKV on the coast. DENV was detected exclusively on the coast. Both viruses were detected in immature mosquitoes of both sexes, providing evidence of transovarial transmission of these arboviruses in local mosquitoes. This phenomenon may be driving underlying viral maintenance that may largely contribute to periodic re-emergence among humans in Kenyaen_US
dc.language.isoenen_US
dc.publisherPLOS NEGLECTED TROPICAL DISEASESen_US
dc.subjecttransovarial transmissionen_US
dc.subjectChikungunyaen_US
dc.subjectDengueen_US
dc.subjectField-caught mosquitoesen_US
dc.subjectKenyaen_US
dc.titleEvidence of transovarial transmission of Chikungunya and Dengue viruses in field caught mosquitoes in Kenyaen_US
dc.typeArticleen_US


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