Diabetes mellitus-a devastating metabolic disorder
Abstract
Diabetes mellitus is an endocrinological and/or metabolic disorder with
an increasing global prevalence and incidence. High blood glucose levels
are symptomatic of diabetes mellitus as a consequence of inadequate
pancreatic insulin secretion or poor insulin-directed mobilization of
glucose by target cells. Diabetes mellitus is aggravated by and associated
with metabolic complications that can subsequently lead to premature
death. This review explores diabetes mellitus in terms of its historical
perspective, biochemical basis, economic burden, management
interventions along with the future perspectives.