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HIV-1 protease inhibitor drug resistance in Kenyan antiretroviral treatment-naive and -experienced injection drug users and non-drug users

dc.contributor.authorBudambula, Valentine
dc.contributor.authorMusumba, Francis O.
dc.contributor.authorWebale, Mark K.
dc.contributor.authorKahiga, Titus M.
dc.contributor.authorOngecha‑Owuor, Francisca
dc.contributor.author. Kiarie, James N.
dc.contributor.authorSowayi, George A.
dc.contributor.authorAhmed, , Aabid A.
dc.contributor.authorOuma, Collins
dc.contributor.authorWere, Tom
dc.date.accessioned2024-02-20T13:22:01Z
dc.date.available2024-02-20T13:22:01Z
dc.date.issued2015
dc.identifier.citationBudambula, V., Musumba, F.O., Webale, M.K. et al. HIV-1 protease inhibitor drug resistance in Kenyan antiretroviral treatment-naive and -experienced injection drug users and non-drug users. AIDS Res Ther 12, 27 (2015). https://doi.org/10.1186/s12981-015-0070-yen_US
dc.identifier.issn1742-6405
dc.identifier.urihttp://ir.tum.ac.ke/handle/123456789/17435
dc.descriptionhttps://doi.org/10.1186/s12981-015-0070-yen_US
dc.description.abstractAlthough injection drug use drives antiretroviral drug resistance, the prevalence of protease inhibitor (PI) resistance among Kenyan IDUs remains undetermined. We, therefore, explored PI resistance mutations and their association with viral load and CD4+ T cell counts in HIV-1 infected IDUs (ART-naive, n = 32; and -experienced, n = 47) and non-drug users (ART-naive, n = 21; and -experienced, n = 32) naive for PI treatment from coastal Kenya.en_US
dc.description.sponsorshipNational Research Funden_US
dc.language.isoenen_US
dc.publisherBioMed Centralen_US
dc.subject: HIV-1en_US
dc.subjectProtease inhibitoren_US
dc.subjectDrug resistanceen_US
dc.subjectAntiretroviraen_US
dc.subjectTreatment-naiveen_US
dc.subjectTreatment-experienceden_US
dc.subjectInjection drug usersen_US
dc.subjectNon-drug usersen_US
dc.subjectCoastal Kenyaen_US
dc.titleHIV-1 protease inhibitor drug resistance in Kenyan antiretroviral treatment-naive and -experienced injection drug users and non-drug usersen_US
dc.typeArticleen_US


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