| dc.description.abstract | Bulbine abyssinica is widely used in folk medicine in Eastern Cape Province,
South Africa. The aim of this study was to evaluate the antifungal and toxicity
potentials of essential oil, acetone and aqueous extracts of this species using
standard procedures and brine shrimp test, respectively. The results showed
that the species was active against the growth of Microsporum canis,
Microsporum gypseum and Trichophyton rubrum among the evaluated
opportunistic fungi. The toxicity results showed that the lowest cysts hatching
success was observed with the essential oil, then acetone extract, with
aqueous extract exhibiting the highest hatching success. Based on the criterion
of toxicity indices of the lethality test, all the plant fractions exhibited LD50
values greater than 1 mg/mL hence are non-toxic. These findings indicate
that B. abyssinica is a good source of antifungal agents. | en_US |
